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Julian Matias Fernandez Boccazzi Barbara Eizaguirre Xavier Merchan-del-Hierro Jose-Luis Etcheverry Natalia Gonzalez-Rojas Victoria Aldinio Martin Cesarini Gabriel Persi Emilia M. Gatto

Abstract

Introduction: Ataxias are a heterogeneous group of disorders with multiple etiologies. Despite the existence of several rating scales, no validated Spanish version of the SARA scale has been available. Given that more than 480 million people worldwide are Spanish speakers, the absence of such a tool represents a gap in clinical practice and research. Methods: The SARA scale was translated and cross-culturally adapted following ITC guidelines. A pilot test was conducted in 13 patients with genetically confirmed (n=11) or immune-mediated (n=2) ataxia. Internal consistency was assessed using Cronbach’s alpha, and external validity was evaluated against Barthel index, disease stage, and disease duration. Results: The Spanish version of SARA showed good internal consistency (Cronbach’s alpha = 0.87). A significant negative correlation with Barthel index (r=-0.94, p<0.01) and a positive correlation with disease stage (r=0.921, p<0.01) were observed. Correlation with disease duration was weak and not significant (r=0.55, p=0.51). Discussion: This pilot study demonstrates the feasibility of a Spanish adaptation of SARA, aligning with results from international validations (Portuguese, Japanese, Chinese, French). Although preliminary, these findings suggest that this tool may provide a reliable measure for clinical and research purposes in Spanish-speaking populations. We generated a Spanish version of the SARA scale with promising preliminary results in terms of reliability and validity. Further multicenter studies with larger cohorts are warranted to confirm its definitive validation.

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How to Cite
Fernandez Boccazzi, J. M., Eizaguirre, B., Merchan-del-Hierro, X., Etcheverry, J.-L., Gonzalez-Rojas, N., Aldinio, V., Cesarini, M., Persi, G., & Gatto , E. M. (2025). Spanish Translation and Pilot Validation of the Scale for the Assessment and Rating of Ataxia (SARA). Journal of Applied Cognitive Neuroscience, 6(2), 1–13. https://doi.org/10.17981/JACN.6.2.2025.6654
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Original Article

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